BCM Home Bellen Lab Home

Tomoko Oyama

Tomoko Ohyama


Contact Information

Tel: (713) 798-6928
Email: toyama@bcm.tmc.edu


Research Interests

I am interested in the molecular mechanisms of neurotransmitter release. I am currently involved in the identification of genes affected by mutations in neurotransmission that were recovered during an eyFLP screen that was recently conducted in the lab.


Publications

Ly CV, Yao CK, Verstreken P, Ohyama T, Bellen HJ (2008) straightjacket is required for the synaptic stabilization of cacophony, a voltage gated calcium channel α1 subunit. Journal of Cell Biology 181:157-170.
Verstreken P, Ohyama T, Bellen HJ (2008) (Book Chapter) FM 1-43 labelling of synaptic vesicle pools at the Drosophila neuromuscular junction. In Exocytosis and endocytosis. Editor: A. Ivanov. Humana Press, Totowa, NJ, pp. 349-369.
Ohyama T, Verstreken P, Ly CV, Rosenmund T, Rajan A, Tien AC, Haueter C, Schulze KL, Bellen HJ (2007) Huntingtin-interacting protein 14, a palmitoyl transferase required for exocytosis and targeting of CSP to synaptic vesicles. Journal of Cell Biology 179:1481-1496.
Bi W, Ohyama T, Nakamura H, Yan J, Visvanathan J, Justice MJ, Lupski JR (2005) Inactivation of Rai1 in mice recapitulates phenotypes observed in chromosome engineered mouse models for Smith-Magenis syndrome. Human Molecular Genetics 14:983-995.
Inoue K, Khajavi M, Ohyama T, Hirabayashi S, Wilson J, Reggin JD, Mancias P, Butler IJ, Wilkinson MF, Wegner M, Lupski JR (2004) Molecular mechanism for distinct neurological phenotypes conveyed by allelic truncating mutations. Nature Genetics 36:361-369.
Unhavaithaya Y, Shin TH, Miliaras N, Lee J, Ohyama T, Mello CC (2002) MEP-1 and a homolog of the NURD complex component Mi-2 act together to maintain germline-soma distinctions in C. elegans. Cell 111:991-1002.

Home Introduction People Publications