Bellen Lab

Jose Salazar

Jose Salazar

BS, Texas A&M University

Research Interests

Alzheimer's disease (AD) affects millions of people in the United States alone. Although genes and mutations that cause early-onset AD have been studied extensively, genetic risk factors of late-onset AD are less understood. I am interested in uncovering the molecular function of TM2D3, a new late-onset AD risk gene, and its related homologs to unravel novel cellular pathways that predispose individuals to AD and related neurodegenerative disorders.

I am co-mentored by Shinya Yamamoto.


Li-Kroeger D, Kanca O, Lee PT, Cowan S, Lee MT, Jaiswal M, Salazar JL, He Y, Zuo Z, Bellen HJ (2018) An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in DrosophilaeLife 7:e38709.  [Abstract]
Salazar JL, Yamamoto S (2018) Integration of Drosophila and Human Genetics to understand Notch signaling related diseases. Advances in Experimental Medicine and Biology 1066:141-185.  [Abstract]
Jakobsdottir J, van der Lee SJ, Bis JC, Chouraki V, Li-Kroeger D, Yamamoto S, Grove ML, Naj A, Vronskaya M, Salazar JL, DeStefano AL, Brody JA, Smith AV, Amin N, Sims R, Ibrahim-Verbaas CA, Choi SH, Satizabal CL, Lopez OL, Beiser A, Ikram MA, Garcia ME, Hayward C, Varga TV, Ripatti S, Franks PW, Hallmans G, Rolandsson O, Jansson JH, Porteous DJ, Salomaa V, Eiriksdottir G, Rice KM, Bellen HJ, Levy D, Uitterlinden AG, Emilsson V, Rotter JI, Aspelund T; Cohorts for Heart and Aging Research in Genomic Epidemiology consortium; Alzheimer's Disease Genetic Consortium; Genetic and Environmental Risk in Alzheimer's Disease consortium, O'Donnell CJ, Fitzpatrick AL, Launer LJ, Hofman A, Wang LS, Williams J, Schellenberg GD, Boerwinkle E, Psaty BM, Seshadri S, Shulman JM, Gudnason V, van Duijn CM (2016) Rare functional variant in TM2D3 is associated with late-onset Alzheimer's disease. PLoS Genetics 12:e1006327.  [Abstract]
Aksoy E, Salazar J, Koiwa H (2014) Cadmium determinant 1 is a putative heavy-metal transporter in Arabidopsis thalianaFASEB Journal 28:617.4.   

Last Modified 3-31-21 by Jodie Hebert

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