Bellen Lab

Jennifer Deger

Jennifer Deger

BSA, University of Texas at Austin


Research Interests

I want to help unravel the mechanisms underlying neurodegenerative diseases that occur with aging, especially Alzheimer's disease. Flies are an incredibly powerful model organism to study human disease. They are extremely genetically tractable, they have complex behaviors and a true central nervous system, and you don't have to wait very long for a fly to get very old! I'm especially interested in how glial biology and the blood-brain barrier change in fly models of Alzheimer's disease and how we can use that knowledge to help human patients.


Publications

Deger J, Goethe E, LoPresti M, Lam S (2020) Intraventricular Hemorrhage in Premature Infants: A Historical Review. Journal of Neurosurgery: Pediatrics :in press.   
Rousseaux G, Vazquez-Velez G, Al-Ramahi I, Jeong H, Baji A, Revelli J, Ye H, Phan E, Deger J, Perez A, Kim J, Lavery L, Xu Q, Li M, Kang H, Kim J, Shulman J, Westbrook T, Elledge S, Liu Z, Botas J, Zoghbi H  (2018) A druggable genome screen identifies modifiers of alpha-synuclein levels via a tiered cross-species validation approach. Journal of Neuroscience 38:9286-9301.  [Abstract]
Deger J, Gerson J, Kayed R.  (2015) The interrelationship of proteasome impairment and oligomeric intermediates in neurodegeneration. Aging Cell 14:715-24.  [Abstract]

Last Modified 3-31-21 by Jodie Hebert

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