Bellen Lab

Debdeep Dutta

Debdeep Dutta

BSc, University of Burdwan, West-Bengal, India
MSc, Banaras Hindu University, India
PhD, Banaras Hindu University, India (Ashim Mukherjee)

Research Interests

My research interest is to understand the pathobiology of rare and undiagnosed neurological diseases. By taking advantage of next-generation sequencing data of the patients and the success of variant functional assessment using the humanized fruit-fly model, I will identify novel human disease genes. Importantly, I will further dissect the biological mechanisms of these new disease genes with a particular focus on conserved signaling pathways. Unraveling the biology of rare neurological conditions can be immensely helpful for the therapeutic development and proper disease management; and, it will also shed light on more common disease mechanisms.


Publications

Dutta D, Mutsuddi M, Mukherjee A (2018) Synergistic interaction of Deltex and Hrp48 leads to JNK activation. Cell Biology International 43:350-357.  [Abstract]
Paul MS, Dutta D, Singh A, Mutsuddi M, Mukherjee A (2018) Regulation of Notch signaling in the developing Drosophila eye by a T-box containing transcription factor, Dorsocross. Genesis 56:e23251.  [Abstract]
Dutta D, Singh A, Paul MS, Sharma V, Mutsuddi M, Mukherjee A (2018) Deltex interacts with Eiger and consequently influences the cell death in Drosophila melanogasterCellular Signalling 49:17-29.  [Abstract]
Paul MS, Singh A, Dutta D, Mutsuddi M, Mukherjee A (2018) Notch signals modulate lgl mediated tumorigenesis by the activation of JNK signaling. BMC Research Notes 11:247.  [Abstract]
Singh A, Dutta D, Paul MS, Verma D, Mutsuddi M, Mukherjee A (2018) Pleiotropic functions of the chromodomain-containing protein Hat-trick during oogenesis in Drosophila melanogasterG3 (Bethesda) 8:1067-1077.  [Abstract]
Dutta D, Paul MS, Singh A, Mutsuddi M, Mukherjee A (2017) Regulation of Notch signaling by the heterogeneous nuclear ribonucleoprotein Hrp48 and Deltex in Drosophila melanogasterGenetics 206:905-918.  [Abstract]

Bellen Lab
1250 Moursund St., Suite N1125 - Houston, TX 77030

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