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Colleen Brady

Colleen Brady



Research Interests

Cell adhesion molecules and axon guidance molecules are important for the proper wiring of the nervous system and the formation of stable synapses. Mutations in these can lead to defects in synaptogenesis and in the formation of neural circuits, and it is thought that these processes are disrupted in neurodevelopmental disorders. I am interested in identifying novel cell adhesion molecules that play a role in the wiring of the nervous system with the goal of identifying new genes that may be involved in the pathogenesis of neurodevelopmental disorders.


Publications

Sun LO, Brady CM, Cahill H, Al-Khindi T, Sakuta H, Dhande OS, Noda M, Huberman AD, Nathans J, Kolodkin AL (2015) Functional assembly of accessory optic system circuitry critical for compensatory eye movements. Neuron 86:971-984.  [Abstract]
Riccomagno MM, Sun LO, Brady CM, Alexandropoulos K, Seo S, Kurokawa M, Kolodkin AL (2014) Cas adaptor proteins organize the retinal ganglion cell layer downstream of integrin signaling. Neuron 81:779-786.  [Abstract]
Sun LO, Jiang Z, Rivlin-Etzion M, Hand R, Brady CM, Matsuoka RL, Yau KW, Feller MB, Kolodkin AL (2013) On and off retinal circuit assembly by divergent molecular mechanisms. Science 342:1241974.  [Abstract]