Michael Wangler

Contact Information

Tel:	(713) 798-4396
Email:	mw147467@bcm.edu

Research Interests

I am a clinical fellow in the Department of Molecular and Human Genetics having recently completed residency training in pediatrics. I have previously conducted research in genetic epidemiology. I am training to become a clinical specialist in pediatric genetic diseases and inborn errors of metabolism. I have joined the Bellen Lab because of the powerful genetics tools that Drosophila melanogaster provides, and because of the Lab's experience and success in assessing the development, physiology and resilience of the Drosophila nervous system. Specifically, stimulated by a recent clinical experience, I am using Drosophila as a model for the study of peroxisomal disorders, both involving biogenesis and specific enzymatic defects. I hope this effort will add to ongoing work in other organisms to better understand these complex and devastating diseases.

Publications

Plunkett J, Feitosa MF, Trusgnich M, Wangler MF, Palomar L, Kistka ZA, DeFranco EA, Shen TT, Stormo AE, Puttonen H, Hallman M, Haataja R, Luukkonen A, Fellman V, Peltonen L, Palotie A, Daw EW, An P, Teramo K, Borecki I, Muglia LJ (2009) Mother's genome or maternally-inherited genes acting in the fetus influence gestational age in familial preterm birth. Human Heredity 68:209-219.

Kistka ZA, Palomar L, Lee KA, Boslaugh SE, Wangler MF, Cole FS, DeBaun MR, Muglia LJ. (2007) Racial disparity in the frequency of recurrence of preterm birth. American Journal of Obstetrics and Gynecology 196:131.e1-6.

Wangler MF, An P, Feinberg AP, Province M, Debaun MR (2005) Inheritance pattern of Beckwith-Wiedemann syndrome is heterogeneous in 291 families with an affected proband. American Journal of Medical Genetics, Part A 137:16-21.

Wangler MF, Chang AS, Moley KH, Feinberg AP, Debaun MR (2005) Factors associated with preterm delivery in mothers of children with Beckwith-Wiedemann syndrome: a case cohort study from the BWS registry. American Journal of Medical Genetics, Part A 134A:187-191.

Chang AS, Moley KH, Wangler MF, Feinberg AP, Debaun MR (2005) Association between Beckwith-Wiedemann syndrome and assisted reproductive technology: a case series of 19 patients. Fertility and Sterility 83:349-354.